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hematology diagnosis differential management thrombocytopenia causes disorders anemia coagulation treatment pathophysiology teg thromboelastography workup bleeding blood comparison purpura table thromboelastogram
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... differential #diagnosis #hematology
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
children) • Platelets ... extremely low platelet ... Diagnosis #Overview #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis Platelet ... Diagnosis #causes #Platelets ... #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... #disorders #hematology
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... treatment #diagnosis #hematology
Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... Management #Diagnosis #Hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
A Classification of Coagulation Disorders #Coagulation #Disorders #Classification #Platelet #Classification #Differential #Diagnosis
A Classification ... Coagulation #Disorders #Classification ... #Platelet #Classification
Formation of a Hemostatic Platelet Plug #Hemostatic #Platelet #Plug #Formation #Pathophysiology #Hematology
of a Hemostatic Platelet ... #Hemostatic #Platelet ... Pathophysiology #Hematology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT) • Suspected HIT Algorithm • "4 T's" clinical probability score:
Suspected HIT Algorithm ... Thrombocytopenia (platelet ... Timing of onset of platelet ... Thrombocytopenia #HIT #hematology ... diagnosis #4Ts #algorithm
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