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diagnosis dermatology differential generalized oncology rheumatology skinrash systemic dermatologic eczematous globulin gpa granulomatosis leukemia mds myelodysplasia myelodysplastic nonpalpable palpable papulosquamous
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... renal failure/uremia ... Myelodisplastic syndrome ... #primary #secondary ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Skin Lesion - Differential ... renal failure/uremia ... Myelodisplastic syndrome ... #secondary #systemic ... #causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... associated with pruritus ... • Goodpasture syndrome ... #dermatology #rash
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... in primary or secondary ... deficiency Work ... cryoglobulins • Skin ... #Causes #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... - Hemolytic anemia ... vasculitis - GPA ... Differential #Diagnosis #hematology
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin ... Rash - Differential ... Eczematous - Pruritic ... Secondary to venous ... #causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Planus - Purple, pruritic ... central clearing • Secondary ... #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... DDX: Rule Out Secondary ... Causes • Anemia ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... - infiltrates (anemia ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia
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