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diagnosis hematology anthracycline cardiotoxicity chronic cll leukemia lymphocytic management mds myelodysplasia myelodysplastic pharmacology plasmacytoma solitary syndromes toxicity
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Cytotoxic drugs/Chemotherapy ... anemia Treatment ... #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... ) • Intensive chemotherapy ... diagnosis #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... Bone marrow Treatment ... • Surgery and chemotherapy ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
) and initiate treatment ... monitoring is not well ... Cardiotoxicity #cardiology ... #oncology #pharmacology ... #toxicity #chemotherapy
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