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diagnosis betadglucan cns fungal galactomannan laboratory neurology sensitivity aids algorithm aspergillus biomarkers calculation comparison dehydrogenase elevated encephalitis epidemiology falsepositives formulas
Sensitivity is the proportion of truly diseased persons in the screened population who are identified as
Specificity is the ... #Sensitivity #Specificity ... #PositivePredictiveValue ... #NegativePredictiveValue
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 CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... sensitivity 100%, specificity ... at 50–90%, but specificity ... 80–90%, and a specificity ... #differential #
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Sensitivity & Specificity ... 96% - Higher specificity ... invasive fungal infection ... surfaces - Infections ... BAL GM does not differentiate
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... sensitivity and specificity ... sensitivity and specificity ... rav7ks #CNS #Infections ... #differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... sensitivity and specificity ... • Toxins • Infection ... Dehydrogenase #Elevated #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Infectious ... Assists in liver specificity ... injury #hepatitis #differential
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Testing Sensitivity Specificity ... 96% • Higher specificity ... surfaces, Albumin, Infections ... in BAL does not differentiate
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • Viral infections ... heavy/light chain specificity ... Gap #ProteinGap #differential
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