6 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... • Leukocoria (absent ... partial retinal red reflex ... pathophysiology #ophthalmology ... #diagnosis #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
unresponsiveness; the absence ... Differential Diagnosis ... • Examine for signs ... #PhysicalExam #neurology ... #comatose #diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... required +/- prompt ophthalmology ... depending on presence/absence ... GCA #Temporal #Signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... inhibitors • Uveitis- Ophthalmology ... #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... neuropathy • Absent ... affects the skin, neurologic ... cognitive impairment, neurologic
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... : decreased or absent ... bouts of HTN Diagnostic ... • Bilateral signs ... #management #neurology