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diagnosis rheumatology differential syndrome demyelinating diseases erythematosus histiocytosis igg4 immune inflammatory iris langerhans lch lupus neurology reconstitution sjogrens sle systemic
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Key Features ... • Pancreas: Type ... Thyroid (Riedel's), CNS ... complement • Classification ... IGG4 #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
IV RTA, TYPE I ... ducts Clinical Features ... nervous system (CNS ... • 8%-27% for CNS ... Rheumatology #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Kikuchi disease • Type-I ... Angioimmunoblastic T-cell ... and CNS • Headache ... : • Chronic B-cell
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
increase in CD4+ cells ... onset of illness features ... Related to the type ... pleural effusions, CNS ... Differential #Diagnosis #Management
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM What Are Demyelinating Diseases? • Conditions that damage myelin, the protective
nervous system (CNS ... Oligoclonal bands, cell ... • Clinical Types ... - Symptom management ... spinal cord, area postrema
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans Cell ... , a type of dendritic ... : LCH exhibits features ... CNS involvement: ... Histiocytosis #Diagnosis #Management
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