27 results
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Monoarthritis • Septic ... Crystalline - Gout ... within 1 month of infection ... Erythematosus (SLE), should ... Joint #Disorders #msk
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... (1 joint): • Septic ... • WBC >20k: Septic ... #Joint #Pain #MSK ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
axial (spine, shoulders ... - Autoimmune Rheumatologic ... Disease OLIGOARTHRITIS ... Differential #Diagnosis #MSK ... #rheumatology #
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... Must rule out other ... #AOSD #rheumatology ... #diagnosis #management ... #treatment
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... NMO-IgG (anti-AQP4) should ... , MOG-IgG test should ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Lung cancer • Septic ... HIV-infected patients should ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : • Infection ... should be diagnosed ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Lung cancer • Septic ... HIV-infected patients should ... TB #Diagnosis #Management ... #Treatment #ActiveTB
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
weird joints (shoulders ... • Underlying disease ... states Pathophysiology ... Wrist, MCP, or shoulder ... #Comparison #rheumatology