9 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... terminal alveoli and are ... inhibitors • Injection ... involvement • Other organ ... Can involve any organ
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... terminal alveoli and are ... inhibitors • Injection ... involvement • Other organ ... Can involve any organ
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in Tuberculosis ... PE: - Local ... decreased reflexes Pathophysiology ... Mycobacterium tuberculosis ... excisional biopsy - Detection
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
LATENT TB • ... IGRA/QuantiFERON-TB ... age ACTIVE TB ... single specimen are ... Testing #Diagnosis #Workup
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
individual with active TB ... consistent with old TB ... kidney disease and are ... Underweight • Injection ... individuals #Tuberculosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... (common causes are ... indicated • For organ-specific
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... mixed GH & PRL) ... Diagnosis and Workup ... Transsphenoidal surgical resection ... Endocrinology #Treatment #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... Symptoms: • 50-60% are ... Lymphoma and solid organ ... cholangitis #diagnosis #workup
Fever of Unknown Origin (FUO) Diagnostic Algorithm
STEP 1 Perform a comprehensive history and complete physical examination.
STEP
Fever of Unknown Origin ... FUO) Diagnostic Algorithm ... with microscopy, tuberculosis ... skin test or TB ... Fever #Unknown #Origin