10 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
syndrome, caused ... differentiating between the diagnosis ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
commonly through its ... Rarely dominate the clinical ... Differential Diagnosis ... • Goodpasture syndrome ... #rash #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Positive Coombs testing ... post infectious setting ... hemolytic #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
on bone marrow leading ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Oncology #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... • Difficulty breathing ... Anemia #oncology #hematology ... #diagnosis #management
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... is clinical & labs ... effective, and its ... migrans #skinRash #dermatology ... #clinical #photo
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... Clinical Presentation ... Fever is the main clinical ... nervous system (CNS ... #Diagnosis #Management
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... immunosuppressed pts ... present as non healing ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... membrane bleeding and skin ... Marfan syndrome, ... peds #pediatrics #diagnosis ... #hematology #primarycare
Uremic frost on the forehead.

Full blown uremic syndrome of chronic kidney disease (CKD) is seldom seen
Full blown uremic syndrome ... crystals on the skin ... frost can make its ... diagnosis easy. ... #head #Uremia #clinical