11 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
commonly through its ... Rarely dominate the clinical ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... Petechial or purpuric rash ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Symptoms of anemia ... anemia • Cold ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
patients • Avg age ... to 8 years Clinical ... autoimmune hemolytic anemia ... IgA and/or IgM, age ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
Acute Generalized Exanthematous Pustulosis (AGEP)

AGEP is largely a clinical diagnosis based on classical skin findings in
a clinical diagnosis ... Clinical Presentation ... to 7 days after its ... Exanthematous #Pustulosis #Dermatology ... #diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
has a bimodal age ... Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... Bleeding Disorders Age ... Marfan syndrome, ... peds #pediatrics #diagnosis ... #hematology #primarycare
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Because the median age ... at diagnosis of ... disease tolerate anemia ... importance of clinical ... #algorithm #hematology