21 results
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... iron #deficiency #CHF ... #management #cardiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... #diagnosis #comparison
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
this interesting case ... Diagnosis was made ... testing and expedite treatment ... • Symmetric abnormal ... • Dec NAA, inc Cho
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... sepsis), PE, DAH, CHF ... Renal Failure Treatment ... 500 mg QD until normal
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... can have extra nodal ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... excrete water normally ... Then, ask 3 questions ... the underlying cause ... include vaptans (HF
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Guillain-Barre Diagnosis ... PROTEIN - NORMAL ... #management #treatment
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
Disease (HADD) - MSK ... Radiology Imaging ... • Treatment for ... Differentiate low-signal normal ... #diagnosis #msk
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... - APTT < 1.5 x normal ... #Coagulation #diagnosis ... #causes #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... protein with a normal ... - Of note, normal ... the underlying pathophysiology ... and cauda equina TREATMENT