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management hematology hemophagocytic lymphohistiocytosis rheumatology brain chf criticalcare crypto cryptococcal differential foamed heartfailure icu macrophage mas meningitis mri pharmacology radiology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... following: • Fever ... • Bicytopenia Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... syndromes Clinical ... is the main clinical ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... acute coronary syndrome ... & Dry” is the treatment ... #algorithm #management ... #cardiology #treatment
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... are common but fever ... Standard treatment ... T2 #MRI #Brain #clinical ... #radiology
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