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diagnosis differential rheumatology algorithm management treatment cardiology neurology systemic arthritis classification cns cryofibrinogenemia cryoglobulinemia cryoglobulins daytime dermatology ekg electrocardiogram elevation
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Seizure disorders ... autoantibodies that will cause ... Lumbar Puncture, EEG ... APS), Secondary
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Causes of Excessive ... Restless Legs Syndrome ... Medical/Psychiatric ... Disorders (Eg. ... Parkinson's, MS)
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... function test, ANA (e.g ... ), (neurologic/psychiatric ... or if a primary hematologic ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Chronic inflammatory disorders ... (e.g. autoimmune ... Myelodysplastic syndrome ... #hematology #secondary
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... (common causes ... (eg, skin or esophageal ... Differential #diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... • Nephrotic syndrome ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Type III Often Secondary ... (e.g. systemic ... classification #rheumatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
, eg, cyclic neutropenia ... , Kostmann syndrome ... Chediak-Higashi syndrome ... drug reactions - Secondary ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... defect SIGNS/SYMPTOMS ... impairment, Mood disorder ... Signs and symptoms ... progressive decline → Secondary
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