9 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... vomiting • Fatigue Signs ... Reduced libido • Signs ... addisons #disease #endocrinology ... #diagnosis #signs
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... disorders including hypokalemia ... bruit or signs ... Vasculitis • Endocrinologic ... Hypothyroidism, Primary
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
• Insomnia Primary ... ↑ T3 - Mild hypercalcemia ... #differential #endocrinology ... #signs #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
not a feature of primary ... Cataracts Labs: Hypokalemia ... Imaging: 1) Primary ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
To prevent hypokalemia ... patient has good renal ... Signs/Symptoms/Complications ... pathophysiology #endocrinology
Symptoms and Signs of Hypokalemia
Cardiovascular
 - Hypertension
 - Orthostatic hypotension
 - Potentiation of digitalis toxicity
 -
Symptoms and Signs ... of Hypokalemia ... distension - Ileus Renal ... production - Urinary ... #Symptoms #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... tenderness - decreased pulsation ... with GCA or as primary ... Differential #Diagnosis #Rheumatology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
constitutional symptoms ... damage, such as hyperCalcemia ... , Renal insufficiency ... cells < 10% • Urinary ... #Significance #hematology