49 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen ... Pathophysiology EXOGENOUS PYROGEN ... ENDOGENOUS PYROGEN ... CNS - Endogenous Pyrogen ... Pathophysiology #Pyrogen
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
: → Exogenous Pyrogen ... mediators (Endogenous Pyrogen ... → Endogenous Pyrogen ... CNS: Endogenous pyrogen
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
reactivity to pyrogenic
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
• Triggered by pyrogens
“H’s & T’s“ - The reversible causes of Cardiac Arrest 
Hypovolemia, Hypoxia/Hypoxemia, Hydrogen Ion Excess (Acidosis),
Hypoxia/Hypoxemia, Hydrogen
Underlying causes of PEA arrest: H’s and T’s 

Hypovolemia, Hypoxia, Hydrogen Ion (acidosis), Hypo/Hyper-kalemia, Hypothermia
Toxins, Tamponade,
Hypovolemia, Hypoxia, Hydrogen
S1Q3T3 on ECG - Pulmonary Embolism Until Proven Otherwise

- Sam Ghali, M.D.
@EM_RESUS

#S1Q3T3 #ECG #EKG #Electrocardiogram #Cardiology
Embolism Until Proven
H’s and T’s Mnemonic - Causes of Cardiac Arrest
H's - Hypovolemia, Hypoxia, Hydrogen Ions (acidosis), Hyperkalemia
Hypovolemia, Hypoxia, Hydrogen
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Responsive) • GI Hydrogen
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
67% for culture proven ... 48% for culture proven ... 82% for culture proven