57 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pathogenesis and clinical ... ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
Campbell’s sign or Tracheal Descent in Longstanding COPD

Patients with longstanding COPD may show downward displacement of
in Longstanding COPD ... with longstanding COPD ... Tracheal #Descent #COPD ... #clinical #video
Tracheal Descent Sign

Paradoxical inward movement of the trachea during inspiration. Seen in this COPD patient in
Seen in this COPD ... Video via Dr. ... Descent #Sign #clinical ... #video #physicalexam ... breathing #Trachea #COPD
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... Think About CPPD ... Asymptomatic CPPD ... monoarticular CPPD ... #Pseudogout #CPPD
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Hoover’s Sign on Physical Exam

Paradoxical retraction of the lower intercostal spaces on inspiration in this patient
patient in severe COPD ... #PhysicalExam #clinical ... #video #pulmonary ... #COPD #respiratory
Hoover's Sign

Hoover’s sign refers to inward movement of the lower rib cage during inspiration- instead of
associated with COPD ... COPD, and more specifically ... Sign #Pulmonary #COPD ... #PhysicalExam #Video ... #Clinical #Breathing
AECOPD 
 Acute exacerbation of chronic obstructive pulmonary disease. 
COPD #clinical
COPD #clinical
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Reduce risk of COPD ... Initiate if severe COPD ... the treatment of COPD ... won’t have any clinical ... #Pharmacology #COPD
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Exacerbation of COPD ... newly diagnosed COPD ... of AECOPD: • Clinical ... MatthewHoMD #COPD