2054 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... activity, reduces pyrophosphate ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Summary - Calcium Pyrophosphate ... Pathophysiology: Pyrophosphate ... calcium to form CPP ... Chronic calcium pyrophosphate ... #Calcium #Pyrophosphate
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Key features on examination in COPD (Chronic obstructive pulmonary disease)

#Diagnosis #PhysicalExam #COPD #Manifestations #Features #Diagram
examination in COPD ... #Diagnosis #PhysicalExam ... #COPD #Manifestations
Hoover's Sign

Hoover’s sign refers to inward movement of the lower rib cage during inspiration- instead of
associated with COPD ... COPD, and more specifically ... Sign #Pulmonary #COPD ... #PhysicalExam #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... PPi (inorganic pyrophosphate
Campbell’s sign or Tracheal Descent in Longstanding COPD

Patients with longstanding COPD may show downward displacement of
in Longstanding COPD ... with longstanding COPD ... Tracheal #Descent #COPD ... trachea #neck #physicalexam
COPD Physical Exam Likelihood Ratios
Barrel Chest - LR 1.5
Pursed Lip Breathing - LR 2.7
Reduced breath sounds
COPD Physical Exam ... SatyaPatelMD #COPD ... #PhysicalExam #
Hoover’s Sign on Physical Exam

Paradoxical retraction of the lower intercostal spaces on inspiration in this patient
patient in severe COPD ... Hoovers #Sign #PhysicalExam ... video #pulmonary #COPD
Tracheal Descent Sign

Paradoxical inward movement of the trachea during inspiration. Seen in this COPD patient in
Seen in this COPD ... clinical #video #physicalexam ... breathing #Trachea #COPD