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activetb diagnosis latenttb management treatment tuberculosis falsepositives fungal galactomannan laboratory sensitivity testing
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Progressive lung ... characteristic features Clinical ... : • Fever • Weight ... assay (IGRA) • PPD
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... • Progressive lung ... characteristic features Clinical ... : • Fever • Weight ... assay (IGRA) • PPD
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
cut-offs defined in clinical ... dx of IA PPV ... >90% (In most clinical ... result in + as long ... blood products #BetaDGlucan
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