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diagnosis adrenal endocrinology insufficiency algorithm primary causes differential management secondary stimulation #adrenals addisons adrenalcrisis comparison contagious contagiousness coronavirus cortisol cosyntropin
Reproductive Number (R0 "R Naught") showing how contagious / transmissible a pathogen is. The R0
Reproductive Number (R0 ... The R0 for Wuhan ... diseases (SARS, MERS, Ebola ... Fatality 5-10 % Ebola ... #table #SARS #Ebola
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
specificity for AI ... > 15 excludes AI ... - Check ACTH ... have diagnosed AI ... primary vs secondary AI
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Axis Response to ACTH ... primary OR secondary AI ... Measure ACTH: ... High = primary AI ... Diagnosis #Algorithm #ACTH
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
insufficiency (AI ... secondary or tertiary AI ... ACTH, adrenocorticotropic ... Diagnosis #Endo #ACTH
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Pathophysiology Primary AI ... be low, while ACTH ... Secondary AI = the ... Low ACTH leads to
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
In secondary AI ... is absent (low ACTH ... diagnostic of AI ... ACTH STIM TEST: ... baseline cortisol and ACTH
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Insufficiency #AI
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
AM cortisol and ACTH ... /dL -> Primary AI ... present - ACTH ... ug/dL Primary AI ... present - ACTH
Infectious Causes of Adrenal Insufficiency Anatomical distribution of vessels to the adrenal makes the gland prone to
virus, Echovirus, Ebola ... Insufficiency #AI
Adrenal Crisis Do not confuse acute adrenal crisis with Addison disease. In 1855, Thomas Addison described a
hydrocortisonr #ACTH ... #AI ##adrenals
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