12 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... of the cell -> Bilateral ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Red Eye - Differential Diagnosis Framework

What?
Redness in the eye can be caused by many conditions and
the eye can be caused ... Common Causes: ... Unilateral or bilateral ... symptoms + duration ... differential #diagnosis #ophthalmology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... diagnosis column Treatment ... #Sclerosis #neurology
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
pathways occur at the retina ... hypothalamus, and visual cortex ... - Autonomic symptoms ... differential #diagnosis #ophthalmology ... #Neurology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Atypical Temporal: Rapid ... Imaging (if atypical symptoms ... CNS inflammatory cause ... Eyecare (prevent corneal ... Diagnosis #Management #Treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... complete paralysis of all ... cardiomyopathy, Horner ... #neurology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... degeneration of dorsal 8 lateral ... or low pit, low retic ... Check for IF ab Treatment ... and need more rapid
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... cortex → Awareness ... : • Bobbing: Rapid ... Casey Albin MD @ ... #PhysicalExam #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
cord resulting in rapid ... monophasic Pathophysiology ... signs and/or symptoms ... Transverse Myelitis Treatment ... diagnosis #management #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... (Cornelia NEJM ... of the steroid treatment ... Treatment of GCA ... required +/- prompt ophthalmology