9 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... Framework Primary ... Single Organ Vasculitis ... Disease • Cogan syndrome ... #dermatology #rheumatology
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Differential Diagnosis ... Anterior Chamber ... • Sjögren’s syndrome ... hyperviscosity syndrome ... #ophthalmology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... vasculitis) • Cutaneous ... white matter, spinal ... inhibitors • Uveitis- Ophthalmology ... signs #symptoms #rheumatology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
- Ocular syphilis ... manifestations including anterior ... and nephrotic syndrome ... roots, causing a syndrome ... Latent #Tertiary #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Strong sign of cutaneous ... with GCA or as primary ... Rash, arthritis Primary ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Differential Diagnosis ... Non-autoimmune rheumatologic ... the context of primary ... #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involvement: May involve anterior ... skeleton-sacroiliac joint and spine ... sites such as the collar ... #Rheumatology # ... diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... Diagnosis: • Dry ... gland) biopsy • Ocular ... skin (xerosis) • Cutaneous ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
leading to a more rapid ... violaceous, nontender cutaneous ... + distinctive primary ... • Tumor lysis syndrome ... #Oncology #Diagnosis