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diagnosis causes algorithm radiology cardiology clinical hematology management radiologyassistant lung table workup cxr rheumatology ctchest hepatology anemia mnemonic neurology nephrology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Atlas #Microscopy #Pathology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Classification #Approach #Differential
The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: •
The differential ... with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC ... Elevated #MCHC #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Macrocytes, Normal RBCs ... Spherocytes, RBC ... ) - Abnormal RBCs ... Normocytic #Anemia #Differential
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
Algorithm and Differential ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... #Macroscopic #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... 3) Internal (RBC ... Smear ↑ abnormal RBCs ... #Hemolysis #Differential
Plasmodium - Identification Algorithm • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
rings, <1/3 size RBC ... Multiple rings/RBC ... rings, ≤ 1/3 size RBC ... trophs, >1/3 size RBC ... Identification #Algorithm #pathology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... symptomatology Differential ... Investigations • Labs: CBC ... proteinuria, dysmorphic RBCs ... Renal #Syndrome #differential
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Hyponatremia - Differential ... lung) - CNS pathology ... hemorrhage) - Pulmonary ... pathology (e.g. ... #Hyponatremia #Differential
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias - Differential ... • Extrinsic RBC ... • Intrinsic RBC ... Hemolytic #Anemias #Differential
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