162 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC ... #Hematology #Diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... on Smear • Chronic ... Decreased RBC ... Spherocytes on Smear ... Algorithm #Causes #Hematology
P. falciparum ring forms on a thin smear

 - Dr. Christina Dean
@deanchr3

#Plasmodium #falciparum #Rings #Smear #Hematology
forms on a thin smear ... falciparum #Rings #Smear ... #Hematology #Microscopy ... #Clinical #Pathology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... Peripheral Blood Smear ... ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
#Body #Bodies #Pathology ... #Hematology #Smear
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... Diagnosis #Algorithm #hematology
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... parasitemia - normocytic RBCs ... multiples per RBC ... rare in blood smears ... Falciparum #Blood #Smear
Plasmodium - Identification Algorithm
 • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
rings, <1/3 size RBC ... Multiple rings/RBC ... rings, ≤ 1/3 size RBC ... Identification #Algorithm #pathology ... #smear #microscopy
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
Leukoerythroblastosis #Hematology ... #Pathology #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
AML #Clinical #Hematology ... #Pathology #Smear