13 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... acid metabolism products ... = nonspecific (nausea ... Diagnosis: Viral Hepatitis ... Pregnancy #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Alcohol-Associated Hepatitis ... Injury (DILI) ... Viral Hepatitis ... #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... Chronic viral hepatitis ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Failure (ALF): ... • Liver injury ... #differential #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2 ... mg/dL) or acute liver ... failure #HepatitisB ... Indications #management #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... failure ... injury, though ... regarding need for treatment ... Diagnosis #Management #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... failure PBC ... obstruction • ALP ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... eruptions, diarrhea, liver
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... eruptions, diarrhea, liver