29 results
Note there is ST depression in aVR, a true sign of Left Main occlusion.  Many
in aVR, a true sign ... aVR is a good ECG ... sign of left main ... #Clinical #EM #IM ... #Cardiology #EKG
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... tissue expansion (e.g ... #FeedbackLoop #endocrinology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Pathogenesis and Clinical ... excess secretion of hCG ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Pathophysiology: ... #PhysicalExam #clinical
Hyperglycemia - Differential Diagnosis Algorithm
Diabetes Mellitus:
 • Impaired Glucose Tolerance
 • Type I Diabetes
 • Type
• Cushing's Syndrome ... agonists • Others Critical ... Hyperglycemia (e.g ... Diagnosis #Algorithm #endocrinology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... neurology #symptoms #signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
illness What: Key signs ... that define the clinical ... syndrome - Does ... illness script (e.g
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... hyperthermia crisis (late sign