13 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... - Bone marrow evaluation ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... metabolic or endocrine disorders ... #diagnosis #testing ... #Rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... value is low, tests ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
the hematologic cancer ... No evidence of anemia ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Neutropenia • Platelet Disorders ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... • Cervical cancer ... #Rheumatology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
prolonged bed rest ... phlebotomy/ blood work ... during clinical evaluations ... of unnecessary diagnostic ... #differential #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... ovarian tumors, lung cancers ... #differential #diagnosis