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differential abnormal causes coagulation prolonged pt activation ana antibodies antinuclear classification cryofibrinogenemia erythematosus lupus macrophage management mas patterns sle syndrome
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... consumption or binding ... associated with systemic ... Prolonged #Causes #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... consumption or binding ... associated with systemic ... Prolonged #Causes #diagnosis ... #differential #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... Hypofibrinogenemia • ↑ PT ↑ PTT ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
physical exam findings ... • Homogeneous: Systemic ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... #rheumatology # ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... progressing GN • New pulmonary ... Differential Diagnosis ... discrepancies Findings ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and laboratory findings ... Differential Diagnosis ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... #Rheumatology
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