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Central distribution is seen in sarcoidosis and cardiogenic pulmonary edema.
Peripheral distribution is mainly seen in cryptogenic
Central distribution ... pneumonia and UIP ... Radiology #Pulmonary #HRCT ... #Differential #Table ... #Distribution #Central
Algorithm for nodular pattern
The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following:
- Look
Algorithm for nodular ... pattern The algorithm ... perilymphatic, random ... nodules along the central ... Radiology #Pulmonary #HRCT
Diagnostic algorithm for idiopathic pulmonary fibrosis, in part adapted from the ATS/ERS consensus statement. HRCT =
Diagnostic algorithm ... HRCT = high-resolution ... pulmonary fibrosis; UIP ... pneumonitis #IPF #UIP ... #Algorithm #Diagnosis
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Miliary TB: random ... Clinical #Radiology #HRCT ... Pattern #Comparison #Table
Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
- Metastases: random ... emphysema: no walls, central ... dot. - LIP #Clinical ... Differential #Comparison #Table
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
is seen in: - UIP ... Radiology #Pulmonary #HRCT ... #Differential #Table
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis on HRCT ... disease comes from HRCT ... On HRCT there are ... low attenuation (table ... in many cases UIP
Basic Interpretation
A structured approach to interpretation of HRCT involves the following questions:
What is the dominant HR-pattern:
reticular
nodular
high
interpretation of HRCT ... perilymphatic or random ... lower zone or a central ... Radiology #Pulmonary #HRCT ... Interpretation #Algorithm
Approach to the diagnosis of chronic hypersensitivity pneumonitis. 
*Consider additional test: bronchoscopy with bronchoalveolar lavage, transbronchial
hypersensitivity pneumonitis; HRCT ... computed tomography; UIP ... pulmonary #diagnosis #algorithm
Figure 3 HRCT-LUS correlation in normal lung, pulmonary congestion, rheumatoid lung disease, idiopathic pulmonary fibrosis.
Notes: (A)
Figure 3 HRCT-LUS ... artifact); (G) UIP ... Clinical #Diagnosis #HRCT ... #Correlation #Table