9 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... rheumatology #diagnosis #differential
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
antineutrophil cytoplasmic antibodies ... ; SLE, systemic ... lupus erythematosus ... Glomerulonephritis #Algorithm ... #Nephrology #Peds
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus ( ... Lymphoproliferative Disorders ... Kumfer @AnnKumfer #Antinuclear ... rheumatology #diagnosis #differential
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear ... #erythematosus
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Photosensitivity 29% - Raynaud's ... Auto-Antibodies ... Lupusreference #SLE ... #Erythematosus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... ) • Endocrine disorders ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... Erythematosus ( ... SLE), should have ... #msk #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Vasculitis - Collagen disorders ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus ( ... SLE) - Antinuclear ... double-stranded DNA antibodies ... metabolic or endocrine disorders