8 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV-Associated CNS Opportunistic ... Most CNS opportunistic ... • CNS opportunistic ... required until immune ... - Generally >3 cm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... that disrupts immune ... +: Virus (EBV, CMV ... , HHV8,...), Bacteria ... or biologics (CMV
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS
Preventing Bacterial Enteric Illness:
 • Antimicrobial
Enteric Infections ... (CDI): • Vancomycin ... Treatment #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... reconstituted immune ... , bacterial superinfection ... keratitis, iritis • CMV ... - Retinitis, immune
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
Cytomegalovirus Infections ... ART to maintain CD4 ... control of the infection ... Treatment #management #opportunistic ... #pharmacology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Vasculitis • Infectious ... Polymyositis • Immune ... Coxsackie, HIV, CMV ... , EBV - Bacterial ... Up: • Chem: CPK
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
optimize ART with immune ... restoration to CD4 ... Treatment #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
IDSA Recommendations for Preventing and Managing Cryptosporidiosis in HIV-AIDS
Preventing Chronic Cryptosporidiosis:
 • Because chronic cryptosporidiosis occurs
optimize ART for immune ... restoration to CD4 ... Treatment #management #opportunistic ... #infections #HIVAIDS ... #pharmacology