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management infections hivaids idsa prevention diagnosis differential aids cns cryptosporidiosis cytomegalovirus enteric hemophagocytic hiv hlh infectiousdiseases inflammatory iris lymphohistiocytosis microsporidiosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... reconstituted immune ... drug-resistant infection, bacterial ... keratitis, iritis • CMV ... #IRIS #Immune
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... that disrupts immune ... +: Virus (EBV, CMV ... , HHV8,...), Bacteria ... or biologics (CMV
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
: • Most CNS opportunistic ... • CNS opportunistic ... Antimicrobial treatment ... required until immune ... - Generally >3 cm
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS Preventing Bacterial Enteric Illness: • Antimicrobial
Preventing and Treating Bacterial ... difficile Infection (CDI ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
ART to maintain CD4 ... whenever feasible, treatment ... effective for treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS Preventing Chronic Microsporidiosis: • Because chronic microsporidiosis occurs
optimize ART with immune ... : • The best treatment ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Cryptosporidiosis in HIV-AIDS Preventing Chronic Cryptosporidiosis: • Because chronic cryptosporidiosis occurs
optimize ART for immune ... restoration to CD4 ... and symptomatic treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
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