1574 results
Cross-Reactivity of Penicillins and Cephalosporins

Cross reactivity of penicillin-allergic patients to cephalosporins has more to do with
Management #Carbapenem #Reaction ... Incidence #PCN #Pharmacology
Drug Treatment of Anaphylaxis and Allergic Reactions
First-Line Therapy 
 - Epinephrine 
 - Oxygen 
 -
Anaphylaxis and Allergic Reactions ... Anaphylaxis #Management #Pharmacology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction ... Pathophysiology #Psychiatry #Pharmacology
Ethacrynic acid - Conversion
Only loop diuretic without a sulfonamide substituent.
Rarely used alternative in patients who have
hypersensitivity reaction ... acid #Conversion #pharmacology
Anisocoria Evaluation Flow Chart - Differential Diagnosis
1. Check pupillary reaction to light 
2. Measure pupil size.
Check pupillary reaction ... CN III Palsy - Pharmacologic
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Immunosuppressant #Drugs #Pharmacology
Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole

Mnemonic - NOT RISKY?

N - Neurologic
hypersensitivity reactions ... #SideEffects #Pharmacology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
22% - Infusion reaction ... Siltuximab #COVID19 #Pharmacology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... - Mechanism of Action ... - Mechanism of Action ... Acute transfusion reaction ... hypersensitivity #reactions
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Penicillin-induced drug reaction ... Erythematosus, Reactive ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions