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diagnosis management toxicity anthracycline aplastic cancer cardiology cardiotoxicity cell chronic cll cyp3a4 doac hemeonc her2 inducers inhibitors interactions leukemia lymphocytic
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... Interactions #Table #Pharmacology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... benefit of immediate chemotherapy ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Testicular Cancer - Treatment Related Toxicities Bleomycin, Cisplatin, Etoposide, lfosfamide Tinnitus & Hearing Loss Neurotoxicity Pulmonary Fibrosis Hypotension Nephrotoxicity Skin Hyperpigmentation Hemorrhagic Cystitis Myelosuppression Peripheral Neuropathy Ashley
Testicular Cancer - Treatment ... lfosfamide Tinnitus & Hearing ... Testicular #Cancer #chemotherapy ... toxicology #Toxicities #pharmacology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Cytotoxic drugs/Chemotherapy ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... ) • Intensive chemotherapy ... Syndromes #diagnosis #hematology ... #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... Bone marrow Treatment ... • Surgery and chemotherapy ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology ... #toxicity #chemotherapy
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