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diagnosis cardiology cardiotoxicity anemia anthracycline aplastic checkpoint chronic cll cyp3a4 doac hemeonc her2 ici inducers inhibitor inhibitors interactions leukemia lymphocytic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Transformation to large cell ... benefit of immediate chemotherapy ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... Interactions #Table #Pharmacology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... ) • Intensive chemotherapy ... Syndromes #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Cytotoxic drugs/Chemotherapy ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
the periphery, creating ... Bone marrow Treatment ... • Surgery and chemotherapy ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity Problem - Immune checkpoint inhibitors (ICIs) are associated with
events are not well-known ... abatacept for the treatment ... Severity Grading ... #oncology #management ... #treatment
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ) and initiate treatment ... monitoring is not well ... #oncology #pharmacology ... #toxicity #chemotherapy
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