9 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... • Cutaneous small-vessel ... (e.g. systemic lupus ... #classification ... #rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Secondary: CTD: SLE ... Polyarteritis nodosa Large ... #skin #dermatology ... #rheumatology #
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
can affect any type ... #Diagnosis #Rheumatology ... #Differential # ... #Small #Medium ... #Large #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin ... , and SLE) • Urinalysis ... Serologies for Cryoglobulins ... #rheumatology # ... classification
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Divided Into Two Types ... malignancies, vasculitis ... to medium-sized ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Disease Classification ... Kikuchi disease • Type-I ... and large bowel ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
multiple organs, small-vessel ... large-vessel vasculopathy ... Medium and large ... Behcet disease) Differential ... signs #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... primary condition MEDIUM ... and infarcts SMALL ... Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... nervous system: small-fiber ... : • 7%, Cryoglobulinemia ... cell lymphoma • Large ... Sjogrens #Syndrome #Rheumatology