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Action potential in cardiomyocytes The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
phase Phase 0: Depolarization ... Phase 1: Early repolarization ... phase Phase 3: Repolarization ... Myocytes #Phases #Depolarization ... #Repolarization
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Phase I - Initial Repolarization ... Delays ventricular repolarization ... - Ventricular Repolarization ... prolong AV node repolarization ... prolong AV node repolarization
Differential Diagnosis for ST Segment Elevations - ACUTE STEMI - PULMONARY EMBOLISM - LBBB
EMBOLISM - LBBB (PACEMAKER ... - BENIGN EARLY REPOLARIZATION
Action Potential: Depolarization and repolarization of a neuron #ActionPotential #Depolarization #Repolarization #Neuron #Neurology #Pathophysiology
Action Potential: Depolarization ... and repolarization ... ActionPotential #Depolarization ... #Repolarization
Pacemaker Operating Modes 1 - Chamber paced A (atrium), V (ventricle), D (dual/both) 2
Pacemaker Operating ... response has no clinical ... period of time the pacemaker ... would trigger pacemaker-mediated ... The voltage the pacemaker
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
and magnitude of depolarization ... phase 4 to slow depolarization ... prolong AV node repolarization ... interval (delays time repolarization ... prolong AV node repolarization
Temporary / External Pacing • Transvenous & epicardial pacing are temporary methods of supporting brady- &
permanent implanted pacemaker ... required to trigger depolarization ... to identify a depolarization ... MD @nickmmark #pacemaker
Class I Antiarrhythmics and their Key Pharmacologic Properties Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer") Class IB
for the rapid depolarization ... • Slows depolarization ... involved in phase 3 repolarization ... • Prolongs repolarization
Major electrocardiogram findings induced by left ventricular hypertrophy (LVH) An increase in left ventricular mass augments the
alteration in repolarization ... in left atrial depolarization
Differentiating Pacemaker vs ICD on Chest XRay - Single Chamber PPM - Single Chamber ICD -
Differentiating Pacemaker ... KhurrumKhanMD #Pacemaker ... Radiology #comparison #clinical
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