13 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... should be diagnosed ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Nicolas Taar ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Posterior Glenohumeral Joint Shoulder Injection 

Glenohumeral joint injection from posterior approach is easily learned. I do
full thickness tear ... #procedure #clinical ... #video #rheumatology ... #msk #orthopedics ... #sports #physicalexam
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... Albuminuria, nephrotic syndrome ... ulcerated • MSK ... Late latent >1 year ... stages #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
cases/100,000 per year ... Guillain-Barre Clinical ... • Weakness: Starts ... #diagnosis #management ... #treatment #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(Clinical Dx). ... Giant retinal tears ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... of infections) ... month at least 1 year ... #diagnosis #management ... #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... NMO-IgG (anti-AQP4) should ... , MOG-IgG test should ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... Dual-energy CT → MSU ... 2 attacks in a year ... #treatment #rheumatology