13 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
validated for VTE treatment ... studies suggest net clinical ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology ... #Diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
, but without treatment ... reddish brown spots ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
: • Clinical Suspicion ... → Calculate 4T score ... • If 4T score ... #Management #Treatment ... #Hematology #HemeOnc
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
ringworm, was diagnosed ... after 1 week of treatment ... #clinical #photo ... #NEJM #tinea #capitis ... #ringworm #derm
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
the palms and soles ... : • A clinical ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... large total body stores ... • P/E - GI and derm ... Check for IF ab Treatment ... consider other diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... Histoplasmosis Diagnosis ... has five major clinical ... fungal stain of clinical ... Inhalation of spores
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
A diagnosis of pyoderma ... second most common dermatologic ... #clinical #photo ... #NEJM #pyoderma ... ulcerative #colitis #derm
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... used in primary treatment ... #NEJM #clinical ... #photo #lichen # ... planus #derm #wickhams