7 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Hypocalciuria (spot urine ... ratio 0.5%) Differential ... tachycardia • Seizures ... #nephrology #management
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... LiCl use The urine ... Urine chloride is ... #nephrology #differential
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... • Diarrhea A urine ... , Gitelman syndrome ... diagnosis #Algorithm #differential ... #potassium #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... Alkalosis: Differential ... furosemide-like lesion) • Gitelman ... #Alkalosis #Differential ... Diagnosis #Causes #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Hypomagnesemia - Metabolic ... Elevated Renin Urine ... History: - Age >3
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Heat stroke - Metabolic ... exertion/training - Seizures ... obstruction 3. ... causes #treatment #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... , Heat stroke, Metabolic ... exertion/training, Seizures ... hour with goal urine ... Dialysis for severe hyperkalemia