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diagnosis causes algorithm alkalosis management classification elevation lactate lactic low pathophysiology potassium rhabdomyolysis typea typeb urinary
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Hypocalciuria (spot urine ... Renal tubular acidosis ... tachycardia • Seizures ... #nephrology #management
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... Urine chloride is ... urine chloride ... #nephrology #differential
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... , Gitelman syndrome ... acidosis: Proximal ... diagnosis #Algorithm #differential ... #potassium #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Alkalosis: Differential ... chronic respiratory acidosis ... furosemide-like lesion) • Gitelman ... #Alkalosis #Differential ... Diagnosis #Causes #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Heat stroke - Metabolic ... exertion/training - Seizures ... Weakness - Dark urine ... #nephrology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... excretion (e.g., urine ... sweat) - its metabolism ... - Shock - Hypovolemia ... - Compartment syndrome
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