12 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup and Differential ... and Screen for HLH ... HLH syndrome 5. ... Cytogenetics and FISH • Acquired ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup and Differential ... and Screen for HLH ... HLH syndrome 5 ... Cytogenetics and FISH • Acquired ... Diagnosis #Algorithm #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... • Bicytopenia Treatment ... Supportive measures and treating ... diagnosis #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Prunelle Getten #AdultOnset ... diagnosis #management #treatment ... #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... EricsMedicalLectures/ #Acquired ... Diagnosis #Management #treatment ... #hematology #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... lymphohistiocytosis (HLH ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... rich classical HL ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... w/in 24 hours) required
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... Behcet disease) Differential ... Arthritis, AS Treatment ... signs #symptoms #rheumatology