3 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Clinical Significance ... a significant clinical ... #cullensign #em ... pancreatitis #cullen #clinical ... peritonitis #IM #FM #ICU
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... Birbeck granules (EM ... TREATMENT OPTIONS ... with appropriate treatment ... Histiocytosis #Diagnosis #Management