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cardiology management cardiomyopathy checkpoint clinical diagnosis echocardiogram hcm hemophagocytic hlh hocm hypertrophic ici lymphohistiocytosis oncology plax pocus rheumatology septal summary
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity Problem - Immune checkpoint inhibitors (ICIs) are associated with
(ICI) Induced Cardiotoxicity ... abatacept for the treatment ... prednisone 1-2 mg/kg ... #ICI #Cardiotoxicity ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... Anti-IFN-y and JAK inhibitors
Septal Hypertrophic Cardiomyopathy (HOCM) 52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) EM resident
EKG nonspecific, ... Serial trops (-) EM ... Metoprolol - VCU ... echocardiogram #plax #cardiology
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