4 results
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... pregnancy, or other causes ... #cullensign #em ... #clinical #image ... peritonitis #IM #FM #ICU
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... • Pulmonary Symptoms ... Birbeck granules (EM ... DIAGNOSIS • Imaging ... TREATMENT OPTIONS
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
(@MarkRamzyDO, EM ... Hamilton, MD (EM ... over the left anterior ... This patient’s clinical ... Most commonly caused