4 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... pregnancy, or other causes ... #cullensign #em ... peritonitis #IM #FM ... #ICU #surgery
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... • Pulmonary Symptoms ... Birbeck granules (EM ... DIAGNOSIS • Imaging ... TREATMENT OPTIONS
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
(@MarkRamzyDO, EM ... Hamilton, MD (EM ... over the left anterior ... This patient’s clinical ... Most commonly caused