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hematology algorithm hepatology causes classification oncology acidosis aplastic ck creatine dili druginduced elevated elevation gap globulin hemeonc hemophagocytic hepatitis hiv
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... #Injury #Differential ... #Diagnosis #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Liver Injury: ... HBV, HCV, HEV, EBV
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... normal - Infection (EBV ... transaminitis #differential ... #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... non-essential drug/HDS treatments ... HBV, HCV, HEV, EBV ... dechallenge • Acute ... #Injury #Diagnosis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... renal injury, Strenuous ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... to BM) • Constitutional ... Treatment: ... oncology #hematology #diagnosis ... #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... workup, including BM ... hemolysis, deficiency anemia ... Rebound effect from treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... or renal injury ... peritonitis - Acute ... 30mmHg) - Severe anemia ... Injury: • Reduced
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Hepatomegaly - Liver ... subset counts ↓ • Liver ... enzymes ↑ • Mild anemia ... Epstein-Barr virus (EBV ... antibody test) Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
quantify renal injury ... antibody, Anti-GBM ... usually low in anti-GBM ... #diagnosis #management ... #treatment
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