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2: central complications creatine cvc differential elevated hemophagocytic hlh infections kinase lines locations lymphohistiocytosis management rct rhabdomyolysis rheumatology selection sites
Central line myth #2: location, location, location By far the best data we have to guide
total of 3471 catheters ... in 3027 adult ICU ... pubmed/26398070 #EBM ... Central #Venous #Catheters ... #CVC #Lines #Rates
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU
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