10 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
vs 24 Hours and Neurologic ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... should be based on clinical ... enhancement on CT ... effect/Edema • EBV ... #Infections #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Clinical Presentation ... dehydrogenase • Positive ... - Mycoplasma, EBV ... younger pts) Differential
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... • Common clinical ... Singh @rav7ks #CNS ... #Infections #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Bedside: ice pack ... Imaging - CT Chest ... Gravis #diagnosis #management ... #neurology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... infection • Family ... Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... hematology #oncology #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Brucellosis - Dengue, EBV ... Myelitis #diagnosis #management ... #neurology #differential
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
Talk to others - infectious ... nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
comprising langerin-positive ... populations) CLINICAL ... CNS involvement: ... Birbeck granules (EM ... Histiocytosis #Diagnosis #Management