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diagnosis hemophagocytic hlh lymphohistiocytosis oncology visualabstract agglutinin aplastic cardiology cardiomyopathy ck classification cold creatine criticalcare differential disease effectiveness elevated evidence
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
Targeted Temperature Management ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... - NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... Clinical Presentation ... Parvovirus B19 - EBV ... #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... Electrolytes: hypo- phos, kalemia
Septal Hypertrophic Cardiomyopathy (HOCM) 52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) EM resident
Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... Cardiomyopathy #HOCM #HCM #clinical ... #echocardiogram
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 Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... dehydrogenase • Positive ... - Mycoplasma, EBV ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... classification #hematology ... #oncology #management
Sepsis - Interventions that do / do not improve outcomes Do: - Have high index of suspicion and
nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Infections (e.g., EBV ... Clinical Presentation ... - Cytopenias (anemia ... #Hematology #HemeOnc
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