7 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
: - Bedside: ice ... aspiration and acute ... precipitated by: Drugs, infection ... #diagnosis #management ... #neurology
Primary and Secondary Headaches - Red Flags and Differential Diagnosis
Red Flags (SNOOP):
S - Systemic		
N - Neurologic
and Differential Diagnosis ... Increased/Decreased ICP ... Hypoglycemia Anatomy - Acute ... primary #secondary #management ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Impairment: • Acute ... Postsynaptic: Myasthenia Gravis ... Coxsackie, HIV, CMV, EBV ... #neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... Symptoms: • Acute ... • Gram stain: Positive ... #neurology #meningitis
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Syndrome (GBS) Acute ... to a preceding infection ... • Most common infection ... intensive care unit (ICU ... #management #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Syndrome - Summary Acute ... response preceding infection ... - HIV, CMV, EBV ... #management #treatment ... #neurology